Adipose-derived stem cells in cutaneous wound repair

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Effects of Human Adipose-derived Stem Cells on Cutaneous Wound Healing in Nude Mice.

BACKGROUND Despite numerous treatments available for deteriorated cutaneous wound healing such as a diabetic foot, there is still the need for more effective therapy. Adipose-derived stem cells (ASCs) are mesenchymal stem cells, which are self-renewing and multipotent. Mesenchymal stem cells have the potential for tissue repair and regeneration. OBJECTIVE To investigate the effects of human A...

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Adipose-Derived Stem Cells, their Secretome, and Wound Healing

Adipose tissue is an abundant source of progenitor cells with multidifferentiation potential and these cells, termed adipose-derived stem cells (ASC), have become an important proposed treatment for use in wound healing. The ability of these cells to increase angiogenesis (vessels arise from other vessels) and vasculogenesis (vessels arise from progenitor cells), produce growth factors and cyto...

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An animal model study for bone repair with encapsulated differentiated osteoblasts from adipose-derived stem cells in alginate

Objective(s): Adipose derived stem cells (ADSCs) can be engineered to express bone specific markers. The aim of this study is to evaluate repairing tibia in animal model with differentiated osteoblasts from autologous ADSCs in alginate scaffold. Materials and Methods: In this study, 6 canine’s ADSCs were encapsulated in alginate and differentiated into osteoblasts. Alkaline phosphatase assay (A...

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The Effect of Transplantation of Collagen Hydrogel with Adipose-Derived Mesenchymal Stem Cells on Burn Wound Healing in Rats

Background: Cell therapy is one of the most challenging methods in the healing of burn wounds in the world. The present study aimed to determine the effect of collagen hydrogel with adipose-derived mesenchymal stem cells on burn wound healing in an animal model. Materials and Methods: The present study was experimentally performed on 24 Wistar rats. Burn wounds were created on the skin of rats...

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Skin wound healing following the spray of human abdominal adipose tissue-derived mesenchymal stem cells in diabetic male rat

Introduction: Diabetes is rising worldwide and impaired wound healing is one of its major complications. This study aimed to determine the effects of adipose-derived mesenchymal stem cells (MSCs) on wound healing in diabetic rats. Materials and Methods: In this experimental study, abdominal adipose tissue was obtained from 10 patients who underwent an abdominoplasty. MSCs were isolated from adi...

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ژورنال

عنوان ژورنال: Plastic and Aesthetic Research

سال: 2018

ISSN: 2349-6150,2347-9264

DOI: 10.20517/2347-9264.2018.26